What Is A Clinical Trial?

A clinical trial is any research study that evaluates interventions to prevent, detect, diagnose, or treat a disease or disorder. In a clinical trial, human participants (or groups of participants) are assigned to one or more interventions to assess the results on health outcomes.

Why Are Clinical Trials Important?

Clinical Trials are important in discovering new treatments to prevent, detect, diagnose or treat Narcolepsy. It is the only process to bring new pharmacological drugs and treatments forward for approval to use within the Narcolepsy community. Without the clinical trials, there is a risk that individuals could be given treatments which have no advantage, waste time and could even be harmful to one’s health. If a treatment has no benefit, or has serious side effects, the treatment may not be further developed.

Ongoing Research

Clinical Trial

Recruiting Participants for the SYMPHONY Study

Falling asleep during the day? Sudden muscle weakness? Wake Up Narcolepsy is collaborating with Axsome Therapeutics on a study to assess the efficacy and safety of AXS-12 (Reboxetine) in patients with narcolepsy (SYMPHONY).

Polaris Clinical Development Program

Find out how you and other people with narcolepsy may benefit from the outcome of the POLARIS studies.

Research Study

Northwestern EXPLAIN-2 Study

The Behavioral Sleep Medicine Lab is researching how relationships are affected by idiopathic hypersomnia and narcolepsy (IH/N).

Psychometric Validation Study of three Patient-Reported Outcome Measures for Narcolepsy (NT2) in the United States

Jazz Pharmaceuticals & IQVIA Research Interview Study

Pathophysiology of Narcolepsy and Idiopathic Hypersomnia: A Multimodal Neuroimaging Study

The research includes an MRI scan session and two (non-consecutive) overnight sleep sessions at our sleep laboratory in Montreal, Canada.

Hypersomnia and Narcolepsy Study is Recruiting Participants

There is a new clinical trial opportunity for PWNs located in Canada.

SWHR Understanding the Impact of Menopause on the Workplace Survey

Fortrea Interview Study of Fatigue in Narcolepsy

CATNAP® Pediatric Narcolepsy Registry

Fact Sheet – Risk Evaluation and Mitigation Strategy (REMS) Programs to Promote Appropriate Medication Use and Knowledge: Patient Experiences with REMS Programs

Pillar Patient Advocates Survey

Participants paid $50.

Boston Children’s Hospital Narcolepsy Research Study for Kids Ages 9 to 17

Validation of Pediatric Narcolepsy Patient Reported Outcomes (PN-PROS)

Canadian Sleep Society: Recruitment of 1000 Families of Children Who Experience Sleeping Problems

Scaling-out Better Nights, Better Days to help children and families go from surviving to thriving during COVID-19.

Patient Experience in Clinical Trials Survey

Please help us improve the clinical trial for patients.

Recruiting Participants with Excessive Sleepiness

WUN is collaborating with Hypersomnia Foundation and Dr. Thanh Dang-Vu to investigate brain regions underlying narcolepsy (with or without cataplexy) and idiopathic hypersomnia.


View a calendar of events being hosted by or attended by WUN.

Narcolepsy 360 Podcast

Listen to our latest podcast or browse the archive.