Ongoing Research

There is a new clinical trial opportunity for PWNs located in Canada.

To be eligible to participate, you must meet the following criteria:

• Diagnosed with narcolepsy and/or idiopathic hypersomnia
• Age between 18-64
• Living in Canada
• Have no other sleep disorders
• Have no psychiatric or neurological disorders
• Not pregnant or breastfeeding
• No use of psychotropic drugs
• Eligible for an MRI scan (no pacemaker or metallic prosthesis)

Compensation will be offered for participation. To apply please contact: hypersomnia.research@gmail.com

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If you or your child are over 16 and have been diagnosed with narcolepsy, you may qualify for a research study.

Managing your narcolepsy symptoms is challenging, so learning all your treatment options is very important. One option to consider is the RESTORE study of an investigational medicine, FT218, which is a once‐nightly formulation of sodium oxybate.

In this study, FT218 will be taken orally once per night, before you go to bed, for up to two years. You’ll be asked to complete in‐person or virtual study visits about four times per year and also complete some brief questionnaires.

Who is eligible to participate in this study?

To qualify, you or your child must:

• Be 16 years of age or older

• Be diagnosed with narcolepsy with or without cataplexy

• Have completed the REST‐ON Study and/or be receiving twice‐nightly sodium oxybate

** Find participating sites at ClinicalTrials.gov NCT#:NCT04451668**

Do daytime “sleep attacks” leave you dreaming about a better treatment for narcolepsy?

Do you have excessive daytime sleepiness from narcolepsy? You may be interested to learn about SUVN-G3031, a research study evaluating an investigational product for narcolepsy with and without cataplexy. Currently, there are treatments available that can increase alertness and improve daytime performance in people with narcolepsy. There are also treatments available to help improve the effects of cataplexy. Doctors continue to research treatments through clinical studies because a single safe and effective treatment for multiple symptoms is still unavailable.

The main purpose of this study is to learn how well the study drug works and how safe the study drug is compared to placebo. A placebo is an inactive material that looks like the study drug but does not contain any active study drug.

What will happen in this study?

If you are eligible to enroll in this study, you will be in this study for approximately 7 weeks, and you will need to come to the study center at least 5 times over this period. You will take either the study drug tablet or a placebo tablet once every day for 14 days. You will stay overnight at the study clinic 3 times for a sleep study and other study procedures. You will also come to the study clinic for a safety follow-up visit.

Who is eligible to participate in this study?

To be eligible for this study, you must be:

• Be between 18 and 50 years of age
• Have a diagnosis of narcolepsy confirmed by a sleep study

This is not a complete list of study requirements. The study doctor will review the full requirements for this study with you.

Qualified participants will receive all study-related exams, care and medications at no cost. Compensation for time and travel may be available.

If you are interested in learning more, visit https://clinicaltrials.gov/ct2/show/NCT04072380?term=suven&cond=narcolepsy&draw=2&rank=1. 

If you or your child have received a diagnosis of narcolepsy or IH within the last year and are between the ages of 8-18 years old, you may be eligible to participate in our research study. We are aiming to improve screening for pediatric narcolepsy and idiopathic hypersomnia. The research study involves filling out quick surveys online about you or your child’s sleepiness. Participation will take between 15-20 minutes in total.

Compensation for participating in the study is $10

For more information please contact us at: 617-919-6212 or email 

NeuroSleepResearch-dl@childrens.harvard.edu                          

Who can participate: We are looking for patients 18 years or more who have been diagnosed with Narcolepsy (with or without cataplexy) or Idiopathic Hypersomnia.

What are the factors that may exclude you from participating? 1- Other sleep disorders, 2- Neurological disorders or head trauma, 3-Psychiatric disorders or use of psychotropic drugs, 4- Pregnancy or breastfeeding and 5-Pacemaker or metallic prosthesis

What will participants have to do?  To investigate brain regions underlying narcolepsy (with or without cataplexy) and idiopathic hypersomnia. This study includes two (non- consecutive) overnight sleep sessions at the sleep laboratory and a MRI scan session.

If you are interested by this study, please contact: Elizaveta Frolova, research coordinator. Email: hypersomnia.research@gmail.com

Who is eligible for this study?

1)       Children between the ages of 6-18 years and their parents/guardians

2)       Children or young adults being treated for narcolepsy

3)       Participants must be able to understand the purpose of the study

If you would like to learn more about the study or are interested in participating, please contact us  at NeuroSleepResearch-dl@childrens.harvard.edu or call 617-355-9184.