Apr 23 2026
Now enrolling: Brilliance clinical studies for narcolepsy

Researchers are looking for adults 18-70 years of age with a diagnosis of narcolepsy type 1 (NT1) or narcolepsy type 2 (NT2) to take part in the Brilliance Studies. The purpose of these studies is to research the safety and effectiveness of an investigational study drug taken by mouth  for the potential treatment of excessive daytime sleepiness (EDS). Individuals with NT1 may be eligible for the Brilliance NT1 Studies, and individuals with NT2 may be eligible for the Brilliance NT2 Study. Orexin is a chemical in the brain that helps regulate the sleep/wake cycle. The investigational study drug, ALKS 2680 (also known as alixorexton), is an orexin 2 receptor agonist that may improve symptoms of sleep disorder, such as EDS, and cataplexy (NT1 patients only).

Individuals will be evaluated by the study team to determine their eligibility to participate in this research. Each individual who qualifies will receive either the study drug or a placebo, as well as study-related medical exams and study-related laboratory tests, at no cost. Compensation for time and travel may also be available.

To learn more:

• Visit BrillianceStudies.com